Future Quest- DC's been on a roll with their Hanna-Barbera properties. Future Quest is probably the best, as it has characters like Jonny Quest, the Herculoids, Space Ghost, etc. all inhabiting the same universe.
The Snagglepuss Chronicles- DC reimagines Snagglepuss as a closeted, Southern gay playwright in the vein of Tennessee Williams living at the height of the 1950's Red Scare.
Scooby Apocalypse- Think Scooby-Doo meets The Walking Dead. Nuff said.
Runaways- Great relaunch of the Brian K. Vaughn comic.
Robotech- A retelling of The Macross Saga, that also reimagines the characters and takes some liberties with the story we all know, making it also a kind of "What If?" comic, as well as a reboot.
BSG Vs. BSG- A miniseries from Dynamite in which the two versions of Battlestar Galactica crossover. Written by Peter David.